{"id":18946,"date":"2025-06-29T09:56:43","date_gmt":"2025-06-29T06:26:43","guid":{"rendered":"https:\/\/drpegahkeramati.com\/%d8%b4%d8%a7%db%8c%d8%b9%d8%aa%d8%b1%db%8c%d9%86-%d8%af%d9%84%db%8c%d9%84-%d8%b3%d9%82%d8%b7-%d9%85%da%a9%d8%b1%d8%b1-%d9%88-%d8%b1%d8%a7%d9%87%da%a9%d8%a7%d8%b1%d9%87%d8%a7%db%8c-%d8%af\/"},"modified":"2025-07-01T08:29:07","modified_gmt":"2025-07-01T04:59:07","slug":"most-common-cause-of-recurrent-miscarriage","status":"publish","type":"post","link":"https:\/\/drpegahkeramati.com\/en\/most-common-cause-of-recurrent-miscarriage\/","title":{"rendered":"The Most Common Cause of Recurrent Miscarriage and Its Treatment Options"},"content":{"rendered":"\t\t
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The Most Common Cause of Recurrent Miscarriage and Its Treatment Options- Dr. pegah keramati<\/a><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Recurrent Pregnancy<\/a> Loss (RPL)<\/strong> is one of the most heartbreaking experiences a woman may face on her journey to motherhood. According to the World Health Organization, recurrent miscarriage<\/a> is defined as two or more consecutive pregnancy losses before the 20th week of gestation<\/strong>. This issue not only presents physical challenges but also brings significant emotional stress to couples.
Fortunately, with advances in modern medical science, many cases of recurrent miscarriage are now diagnosable and treatable.<\/p>

But what is the most common cause of recurrent miscarriage<\/strong>? And how can it be diagnosed and managed effectively?
Let\u2019s explore the answers in this comprehensive article.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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The Most Common Cause of Recurrent Miscarriage<\/a><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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  1. Genetic and Chromosomal Abnormalities<\/strong><\/li><\/ol>

    Approximately 50\u201360% of miscarriages in the first trimester<\/strong> are caused by chromosomal<\/a> abnormalities in the embryo. These abnormalities often occur randomly during cell division. However, in some couples, one of the parents may carry a structural chromosomal issue (such as a balanced translocation) that leads to nonviable embryos.<\/p>

    \ud83d\udccc Diagnosis:<\/strong> Parental karyotyping and, when possible, genetic analysis of the miscarried fetal tissue
    \ud83e\ude7a Treatment:<\/strong>     IVF<\/a> with preimplantation genetic testing (PGT)<\/strong><\/p>

    1. Uterine Structural Abnormalities<\/strong><\/li><\/ol>

      Congenital uterine malformations such as a septate uterus, bicornuate uterus, or intrauterine adhesions (Asherman’s syndrome) may interfere with proper embryo implantation or growth, making them one of the common causes of miscarriage.<\/p>

      \ud83d\udccc Diagnosis:<\/strong> 3D ultrasound, hysterosonography<\/a>, or hysteroscopy
      \ud83e\ude7a Treatment:<\/strong> Corrective       hysteroscopic<\/a> surgery<\/p>

      1. Immunologic and Coagulation Disorders<\/strong><\/li><\/ol>

        Some recurrent miscarriages are due to immune system disorders<\/strong>, such as antiphospholipid syndrome (APS)<\/strong> or inherited thrombophilias. These conditions can cause excessive blood clotting, leading to placental thrombosis and disrupted blood supply to the fetus.<\/p>

        \ud83d\udccc Diagnosis:<\/strong> Coagulation and thrombophilia screening (e.g., APLA, Protein C\/S, Factor V Leiden, etc.)
        \ud83e\ude7a Treatment:<\/strong> Low-dose aspirin, heparin, IVIG, or immunotherapy if needed<\/p>

        \u00a0<\/strong>Hormonal and Metabolic Imbalances<\/strong><\/p>

        Hormonal disruptions, including hypothyroidism<\/strong>, uncontrolled diabetes<\/strong>, or low progesterone levels<\/strong>, may impair the endometrium\u2019s ability to support pregnancy.<\/p>

        \ud83d\udccc Diagnosis:<\/strong> Thyroid function tests, blood sugar levels, progesterone and prolactin levels
        \ud83e\ude7a Treatment:<\/strong> Thyroid hormone replacement, blood sugar control, and progesterone supplementation during the luteal phase or pregnancy<\/p>

        1. Infections and Environmental Factors<\/strong><\/li><\/ol>

          Certain bacterial or viral infections\u2014such as Listeria<\/strong>, Toxoplasma<\/strong>, CMV<\/strong>, or STDs<\/strong>\u2014can lead to miscarriage. In addition, exposure to toxic chemicals<\/strong>, smoking<\/strong>, severe stress<\/strong>, and nutritional deficiencies<\/strong> (e.g., vitamin D or folic acid) are contributing factors.<\/p>

          \ud83d\udccc Diagnosis:<\/strong> Vaginal cultures, TORCH panel, lifestyle evaluation
          \ud83e\ude7a Treatment:<\/strong> Antibiotics, lifestyle modifications, and supplements such as folic acid and vitamin D<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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          Treatment Strategies for Recurrent Miscarriage<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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          \u2705 Comprehensive evaluation by a fertility specialist
          \u2705 IVF with genetic testing (PGT) in cases of chromosomal abnormalities
          \u2705 Hysteroscopic surgery for uterine anomalies
          \u2705 Hormonal treatment and regulation
          \u2705 Medication for immune and clotting disorders with close pregnancy monitoring
          \u2705 Advanced therapies like IVIG<\/strong> or lymphocyte immunotherapy<\/strong> in selected cases<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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          If you or someone close to you is facing recurrent miscarriage<\/strong>, the most important step is identifying the exact cause<\/strong>. Many couples who have suffered multiple losses have gone on to experience successful pregnancies after thorough evaluation and appropriate treatment.<\/p>

          Consulting with a fertility or reproductive specialist and undergoing personalized diagnostic testing can open the door to effective treatment\u2014and restore hope along the path to parenthood.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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          The Most Common Cause of Recurrent Miscarriage and Its Treatment Options- Dr. pegah keramati Recurrent Pregnancy Loss (RPL) is one of the most heartbreaking experiences a woman may face on her journey to motherhood. According to the World Health Organization, recurrent miscarriage is defined as two or more consecutive pregnancy losses before the 20th week […]<\/p>\n","protected":false},"author":1,"featured_media":18878,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[101],"tags":[],"wf_post_folders":[80],"class_list":["post-18946","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-article"],"_links":{"self":[{"href":"https:\/\/drpegahkeramati.com\/en\/wp-json\/wp\/v2\/posts\/18946","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/drpegahkeramati.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/drpegahkeramati.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/drpegahkeramati.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/drpegahkeramati.com\/en\/wp-json\/wp\/v2\/comments?post=18946"}],"version-history":[{"count":14,"href":"https:\/\/drpegahkeramati.com\/en\/wp-json\/wp\/v2\/posts\/18946\/revisions"}],"predecessor-version":[{"id":18963,"href":"https:\/\/drpegahkeramati.com\/en\/wp-json\/wp\/v2\/posts\/18946\/revisions\/18963"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/drpegahkeramati.com\/en\/wp-json\/wp\/v2\/media\/18878"}],"wp:attachment":[{"href":"https:\/\/drpegahkeramati.com\/en\/wp-json\/wp\/v2\/media?parent=18946"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/drpegahkeramati.com\/en\/wp-json\/wp\/v2\/categories?post=18946"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/drpegahkeramati.com\/en\/wp-json\/wp\/v2\/tags?post=18946"},{"taxonomy":"wf_post_folders","embeddable":true,"href":"https:\/\/drpegahkeramati.com\/en\/wp-json\/wp\/v2\/wf_post_folders?post=18946"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}